Zyvox is an effective antimicrobial medication, which belongs to a group of drugs called oxazolidinones. The mechanism of Zyvox action is quite simple – it selectively inhibits the protein synthesis in bacteria. The active component of Zyvox is (s)-linezolid, which is biologically active, and metabolized in the body with the formation of inactive derivatives.
This medication is effective in the treatment of diseases caused by aerobic gram-positive bacteria, such as Staphylococcus (aureus, epidermidis, haemolyticus, lugdunensis), Corynebacterium jeikeium, Streptococcus (agalactiae, intermedius, pneumoniae spp., pyrogenes, viridans), Listeria monocytogenes, Enterococcus (faecalis, faecium, casseliflavus, gallinarum).
Zyvox is also showed high results in the treatment of conditions caused by aerobic gram-negative bacteria, such as Chlamydia pneumoniae, Pasteurella canis, Pasteurella multocida, as well as in the treatment of conditions caused by anaerobic gram-positive and gram-negative bacteria: Peptostreptococcus spp. Bacteroides fragilis, Clostridium perfringens, Prevotella spp.
This medication is usually recommended for the treatment of community-acquired pneumonia, hospital pneumonia, infections of skin and soft tissues, infections caused by Enterococcus spp., infections caused by gram-negative organisms. Zyvox must not be administered by patients with hypersensitivity to linezolid and other components. Although Zyvox is well tolerated; it may cause such side effects as allergic reaction, violations of the gastrointestinal tract - abdominal pain, nausea, vomiting, diarrhea and distortion of the blood picture.
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