Amiokordin is an antiarrhythmic medication of the 3rd generation. This medication has antiarrhythmic, antianginal, antihypertensive, and thyroid-stimulating action. Antianginal effect of Amiokordin contributes to the decrease of the myocardial oxygen demand. Amiokordin works by inhibiting potassium, sodium and calcium channels as well as by blocking the alpha-and beta-adrenergic receptors.

This medication is able to prolong the potential of atrial and ventricular actions as well as the refractory period. Amiokordin decreases automaticity of sinus and AV nodes. Antiarrhythmic effect can be observed in about 7 days after the launch of treatment. The highest effect is reached in 15-30 days of treatment and it maintains for 10-30 days after the treatment cancellation.

In US and Europe Amiokordin is widely used for the treatment of such symptoms as ventricular tachycardia, supraventricular tachyarrhythmia, WPW-syndrome. It is as well used for prevention of ventricular fibrillation and tachycardia (slowing or reducing flicker and flutter, prevention of recurrence).

Amiokordin must not be administered by people who have hypersensitivity to any of its components, including iodine, as well as by those patients who suffer from sinus bradycardia, sick sinus syndrome, severe conduction disturbances, thyroid dysfunction and AV blockage.

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