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A team of scientists from Oxford University in the UK have discovered the reason why people feel drowsier in dim lighting and more alert in bright white light.They have found previously unknown cells in the eye known as the retinal ganglion cells, th ...
Chronic hepatitis B infects 400 million people worldwide, many of them children. Even with three effective vaccines available, hepatitis B remains a stubborn, unrelenting health problem, especially in Africa and other developing areas. The disease an ...
A weather alert service run by the UK's Meteorological Office that forecasts when weather is likely to be bad for COPD patients and alerts them to take simple precautions, has achieved a 20 per cent drop in COPD hospital admissions in areas that ...
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Brand Name: Arava
Manufactured: Aventis
Active Ingredients: leflunomide
Therapeutic actions: This medicine works by stopping the body from producing too many of the immune cells that are responsible for the swelling and inflammation.
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Other names used: • Lefumide
• Leflunomidum
• Lefunomide
What is it used for?
ARAVA is indicated in adults for the treatment of active rheumatoid arthritis (RA):
• to reduce signs and symptoms
• to inhibit structural damage as evidenced by X-ray erosions and joint space narrowing
• to improve physical function.
Contraindications and cautions:
You should not use this medication if you are allergic to leflunomide, or if you are pregnant or may become pregnant.
Before taking leflunomide, tell your doctor if you are allergic to any drugs, or if you have:
• liver disease or a history of hepatitis;
• any type of infection;
• a weak immune system or a bone marrow disorder; or
• if you are using any drugs that weaken your immune system (such as cancer medicine or steroids).
If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.
Side effects: All medicines may cause side effects, but many people have no, or minor, side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using leflunomide and call your doctor at once if you have any of these serious side effects:
• fever, chills, body aches, flu symptoms;
• white patches or sores inside your mouth or on your lips;
• chest pain;
• cough, trouble breathing (you may also have a fever);
• pain or burning when you urinate;
• pale skin, easy bruising or bleeding, unusual weakness;
• nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.
Less serious side effects may include:
• weakness;
• nausea, stomach pain, diarrhea, loss of appetite;
• weight loss;
• headache, dizziness;
• numbness or tingling;
• sore throat, runny or stuffy nose; or
• mild itching or skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
Interactions: Tell your doctor or pharmacist if you are taking any other medicines, including any that you get without a prescription from your pharmacy, supermarket or health food shop.
Before taking leflunomide, inform your doctor if you are taking cholestyramine (Questran, Prevalite, LoCHOLEST) or rifampin (Rifadin, Rimactane).
Also tell your doctor if you are using medications that can weaken your immune system, such as:
• methotrexate (Rheumatrex);
• cyclosporine (Neoral, Sandimmune, Gengraf);
• sirolimus (Rapamune), tacrolimus (Prograf);
• basiliximab (Simulect), efalizumab (Raptiva), muromonab-CD3 (Orthoclone);
• mycophenolate mofetil (CellCept); or
• azathioprine (Imuran), leflunomide (Arava), etanercept (Enbrel).
This list is not complete and there may be other drugs that can interact with leflunomide. Do not start a new medication without telling your doctor.
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Why are branded medicines that you sell so cheap?
We keep low prices because we buy our medicines in the countries, which have a low drug tax, however all medicines are produced by original manufactures. Another reason of low prices is purchasing of the drugs in association with a large group of partners in bulk quantity. Also we use cheaper but quality method of delivery.
Why are generic drugs cheaper than branded medicines?
Manufacturers that produce generics do not spend much money on development of a new preparation, they just need to reproduce something that was developed before. That’s why the price for generics is much more affordable. Usually generics are let to be produced only when the original medication is being sold in the market for several years.
Is Generic the exact copy of the original?
If we study the chemical composition of the generic and the original, we’ll find out that in reality they are not identical (duplicates). They have similar “therapeutic core” but additional ingredients can differ either in quantitative or qualitative composition. Anyway it doesn’t influence the effect.
At the end of the pat
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