Augmentin is a broad spectrum antibiotic, which exerts the bacteriolytic action. Augmentin is highly effective against a wide spectrum of aerobic and anaerobic gram-positive and aerobic gram-negative microorganisms, including strains producing beta-lactamase. The main active ingredients in Augmentin are amoxicillin and clavulanic acid.
Augmentin is usually recommended for the treatment of such infections of the upper and lower respiratory tract as tonsillitis, sinusitis, otitis media, exacerbation of chronic bronchitis, lobar and bronchopneumonia. Clinical trials showed positives results of Augmentin in curing the urinary tract infections: cystitis, urethritis, pyelonephritis, gynecological infections as well as the infections of the skin and soft tissues, bones and joints and even severe infections - septic abortion, obstetric sepsis and intra-abdominal sepsis. Augmentin is also used for perioperative prophylaxis of surgical infection.
Augmentin must not be administered by patients who have hypersensitivity to any of its components as well as by those who suffer from infectious mononucleosis. This medication must be taken with caution by pregnant and breastfeeding women as well as by those persons who suffer from severe hepatic failure or gastrointestinal disease.
This medication is usually taken orally with or without food. The best results are achieved when the dosage is adjusted individually, depending on the severity and location of infection as well as on the sensitivity of the pathogen. Although Augmentin is well tolerated, there still may appear such adverse reactions as nausea, vomiting, diarrhea, abnormal liver function, and in rare cases – hepatitis and pseudomembranous colitis.
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