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Home / Pain relief / Baclofen

Generic Baclofen

 
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Baclofen

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Active Ingredients:
Baclofen

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Product Information

Baclofen is an effective muscle relaxant. The central mechanism of action of Baclofen is that of the derivatives of chlorophenylbutyric acid. This medication significantly reduces the elevated tone of skeletal muscles, majorly caused by the injuries of the spinal cord. Baclofen inhibits the cutaneous reflexes and muscle tone and slightly reduces the amplitude of tendon reflexes.

The muscle relaxant effect is achieved due to hyperpolarization of ascending nerve fibers and oppression of monosynaptic and polysynaptic reflexes at the spinal cord. Baclofen does not affect the processes of neuromuscular transmission.
It is worth to remember that the administration of Baclofen in high dosages may cause suppression of CNS function. After the oral administration Baclofen is quickly and completely absorbed in the gastrointestinal tract. This medication is completely excreted with the urine within 72 hours after administration.

Baclofen is usually recommended for the treatment of such conditions as severe chronic spastic state of skeletal muscle, which occurs as a result of multiple sclerosis or traumatic rupture of the spinal cord. Patients, suffering from the hypersensitivity to any of the drugs components as well as those who suffer from peptic ulcer must not use this medication. Although Baclofen is usually well tolerated, there may appear such side effects as drowsiness, nausea, confusion, headache and insomnia.

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