Cephalexin is an antibiotic of the 1st generation, which is referred to the group of drugs, called cephalosporins. This medication has a broad spectrum of bactericidal action. Cephalexin is effective against a wide row of bacteria sensitive to it, such as staphylococci, streptococci, pneumococci, E. coli, Salmonella, Shigella, Haemophilus influenzae, Proteus, treponema and Klebsiella. Yet, there are some bacteria that are resistant to Cephalexin, such as mycobacterium tuberculosis, enterococci and enterobacteria.
Cephalexin is quickly absorbed from the gastrointestinal tract. The maximum plasma concentration of Cephalexin is achieved in 1-1.5 hours. Cephalexin penetrates all tissues and organs, including the pericardium and pleural membrane. The half-life of this medication is about 50-60 minutes. Cephalexin is excreted mainly through the kidneys.
In US and Europe, Cephalexin is mainly prescribed for the treatment of such health conditions as respiratory tract diseases, caused by pathogens sensitive to Cephalexin - bronchitis, pneumonia, lung abscess, pleurisy, the diseases of the urinary - cystitis, pyelonephritis, etc., and the diseases of the reproductive system, such as vulvovaginitis, endometritis, epididymitis and others.
Clinical trials showed the high effect of Cephalexin in the treatment of such conditions as problems with the upper respiratory tract, such as otitis, pharyngitis and tonsillitis, skin problems, such as cellulitis, pyoderma, abscesses and abrasions and the diseases of the locomotor apparatus – osteomyelitis and arthritis. Although Cephalexin is as a rule well tolerated, there may appear such side effects as dyspepsia, diarrhea, weakness, tremor and vertigo.
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