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Drugmaker Amgen Inc announced yesterday, Monday, that a large trial of its bone drug denosumab increased bone density and cut fractures in men with non-metastatic prostate cancer who were having hormone blocking therapy. A side effect of androgen dep ...
Researchers in France studying over 12,000 couples with fertility problems found that when the man was over 35 pregnancy rates fell and perhaps more surprisingly, miscarriage rates rose, leading them to conclude that the age of the father was just as ...
Data is emerging about use of statins and risk reduction in development of prostate cancer (CaP). How do statins affect PSA?
The authors previously observed that PSA levels decreased upon initiation of statin medications.
Source: medicalnewstoda ...
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Brand Name: Concor
Manufactured: Merck (PTY) LTD
Active Ingradients: Bisoprolol
Therapeutic actions: Bisoprolol is a highly beta1-selective beta-adrenoceptor antagonist with low beta2-receptor affinity. It reduces blood pressure, and by blockade of the cardiac beta1-receptors, it reduces cardiac action, and hence myocardial oxygen demand
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| DRUGS |
FORM |
Q-TY |
PRICE |
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ORDER |
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| Concor 2,5mg |
Tablet |
30 |
17.33 $ |
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| Concor 5mg |
Tablet |
30 |
19.40 $ |
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| Concor 10mg |
Tablet |
30 |
27.55 $ |
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| |
What is it used for?
Concor is indicated in the management of mild to moderate hypertension and angina pectoris.
Contraindications and cautions:
Hypersensitivity to bisoprolol.
Particular caution should be exercised with patients suffering from the following: Asthma, bronchitis, chronic respiratory diseases (See Special Precautions), second and third degree heart block, bradycardia less than 50 beats per minute, peripheral vascular disease and Raynaud's phenomenon.
Uncontrolled cardiac failure excluding that due to hypertrophic obstructive cardiomyopathy.
Not to be used during pregnancy or lactation.
The normal dose should be reduced in elderly patients, or in patients suffering from renal dysfunction.
Patients with metabolic acidosis and sinus bradycardia.
Safety and efficacy in children have not been established.
Side effects:
These include lassitude, dizziness, mild headache, perspiration, bradycardia, sleep disorders, restlessness, cold extremities, nausea, vomiting, diarrhoea and skin rash. Constipation, hypotension, paradoxical hypertension, depression, mass gain, paraesthesia, transient hearing loss, heart block, hallucinations, disturbances of vision, blood disorders, fluid retention, muscle cramps, allergic reactions, metabolic disturbances, alopecia, myopathies and stomatitis may occur. Overt psychosis has been reported with other beta-blockers.
Exacerbation of peripheral vascular disease, or the development of Raynaud's phenomenon (due to the unopposed arteriolar alpha-sympathetic activation), hypoglycaemia, skeletal muscle weakness and gastro-intestinal disturbances may occur during treatment with beta-blockers. Severe peripheral vascular disease and even peripheral gangrene may be precipitated.
Interactions:
It can be dangerous to administer bisoprolol concomitantly with the following medicines:
Hypoglycaemic agents, phenothiazines and various antiarrhythmic agents.
N.B. - Such medicine interactions can have life-threatening consequences. It may enhance the effects of hypoglycaemic agents in patients with diabetes mellitus as well as the effects of myocardial depressants such as lignocaine, procainamide and quinidine.
The effects may be antagonised by beta-adrenoceptor stimulating agents (e.g. isoprenaline). The hypotensive effects may be dangerously reversed by alpha-adrenoceptor stimulants. The vasoconstrictor effects may be dangerously enhanced by alpha-adrenoceptor stimulants. The effects may be enhanced by adrenergic neurone blocking agents such as guanethidine and reserpine.
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Viagra
$1.15
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| Viagra - is the most known and used medicine to treat erectile disfunction. |
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Levitra
$2.05
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Levitra - one of the most known brands indicated for treatment of impotence.
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Kamagra 50mg
$1.24
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Kamagra - is a well known generic which has an excellent effect in tretment of erectile disfunction.
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Celebrex
$2.45
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Celebrex is one of the most effective medecines used to treat pain and inflammantory.
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Why do you have such cheap branded medecines?
We keep low prices because we buy our medecines in the countries, which have a low drug tax, however all medicines are produced by original manufactures. Another reason of low prices is purchasing of the drugs in association with a large group of partners in bulk quantity. Also we use cheaper but quality method of delivery.
Why are generic drugs cheaper than branded medicines?
Manufactureres that produce generics do not spend much money on development of a new preparation, they just need to reproduce something that was developed before. That’s why the price for generics is much more affordable. Usually generics are let to be produced only when the original medication is being sold in the market for several years.
Is Generic the exact copy of the original?
If we study the chemical composition of the generic and the original, we’ll find out that in reality they are not identical (dublicates). They have similar “therapeutic core” but additional ingredients can differ either in quantitative or qualitative composition. Anyway it doesn’t influence on the effect.
At the end of the
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