Furosemide is an effective fast-acting diuretic medication, which works by violating the reabsorption of sodium and chlorine in the large segment of the ascending loop of Henle. Furosemide as well increases the excretion of potassium, calcium and magnesium. Diuretic effect of the drug develops in 30 minutes after oral administration and lasts up to 6 hours.

Furosemide is most frequently indicated for the treatment of such health conditions as edematous syndrome of different genesis, including in chronic heart failure IIB-III stages, nephrotic syndrome, pulmonary edema, post-traumatic cerebral edema, some forms of hypertensive crisis, eclampsia and premenstrual tension syndrome.

This medication must not be administered by people who suffer from renal failure with anuria, hepatic coma and precoma, violations of water-salt metabolism: hypokalemia, hyponatremia, hypovolemia (including those with hypotension), or dehydration. It as well must not be administered by people who have hypersensitivity to sulfonamides and by pregnant women in I and II trimesters of pregnancy.

Furosemide should be indicated with caution for patients with severe cardiovascular disease, long-term therapy with cardiac glycosides, as well as for the elderly patients with severe atherosclerosis.

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