Lopressor is a cardioselective beta1-blocker, which doesn’t perform any intrinsic sympathomimetic activity. Lopressor has antihypertensive, antianginal and antiarrhythmic action. This medication works by decreasing of the automaticity of sinus node, reducing, in such a way, heart rate, myocardial contractility, cardiac output and myocardial oxygen demand. Lopressor as well slows the AV conduction. Another notable effect of Lopressor is inhibiting of the stimulatory effect of catecholamines on the heart during physical and psycho-emotional stress.
At the beginning of the treatment patients may feel a hypotensive effect of Lopressor, which stabilizes by the end of the second week of treatment. In patients suffering from angina, Lopressor reduces the frequency and severity of attacks.
This medication normalizes the heart rate during supraventricular tachycardia and atrial fibrillation. Lopressor limits the zone of ischemia of the heart muscle and reduces the risk of fatal arrhythmias developing; it as well decreases the risk of recurrence of myocardial infarction. If Lopressor is used in small doses it performs more powerful effect on smooth muscles of the bronchi and peripheral arteries than non-selective beta-blockers.
Lopressor is commonly used in the treatment of such health conditions as hypertension, angina, and cardiac arrhythmia, secondary prevention after myocardial infarction, cardiac hyperkinetic syndrome and migraine. The usual dosage of Lopressor is 100 mg per day. It is usually taken 1-2 times a day with or without food. The daily dosage can be gradually increased to 200 mg if needed.
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