Zanaflex is a muscle relaxant medication of the central action. It is referred to the group of drugs, called anticonvulsants. Zanaflex works by suppressing the polysynaptic spinal reflexes and performing antispastic action, which increases muscle tone, relieves spasms and clonic convulsions. After its administration, Zanaflex is rapidly and almost completely absorbed. The maximum plasma concentration can be observed in 1 - 2 hours. Zanaflex and metabolites are wasted in an unmodified form with the urine.
Zanaflex is mainly used for the treatment of painful muscle spasms associated with static and functional lesions of the spine - cervical and lumbar syndromes, and after surgery - apropos of a herniated disc or osteoarthritis of the hip. Clinical trials have showed that besides its primary function, Zanaflex is well as effective in the treatment of such conditions as spasticity caused by multiple sclerosis, chronic myelopathy, degenerative diseases spinal cord, stroke and seizures of central origin.
As a rule Zanaflex is well tolerated, although sometimes, patients may experience drowsiness, fatigue, dizziness, dry mouth, nausea, a slight decrease in blood pressure. If higher doses of the medication are administered, patients may feel muscle weakness, insomnia, hypotension, bradycardia, and in rare cases - a temporary increase in transaminase activity in serum. Zanaflex must not be taken by pregnant or breastfeeding women.
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