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What is Lipitor?
Lipitor is a medicine that helps decrease the level of cholesterol in blood by blocking the cholesterol production in your body. Lipitor is indicated for the treatment of high cholesterol, it helps prevent arteries hardening and heart diseases; therefore, it lowers the risk for heart strokes and attacks, as well as vascular disease.

What is the mechanism of action of Lipitor?
The active ingredient of Lipitor is atorvastatin which belongs to statins drug class. It’s a selective competitive inhibitor of HMG-CoA reductase (HMG-CoA reductase is an enzyme from the liver tissue which plays an important part in the cholesterol production). It lowers the cholesterol level by inhibiting cholesterol and HMG-CoA reductase synthesis in liver and increasing the number of LDL (low density lipoproteins) receptors on the surface of cells, and that leads to the intensified capture and catabolism of LDL. Lipitor reduces the LDL formation, and causes marked and persistent increase in the activity of LDL receptors.

What is the proper dosage of Lipitor?
The drug should be used together with a low-fat diet. The dosage of Lipitor should be determined by your healthcare provider only, the dose and therapy duration depend on your current health status and the condition to be treated with Lipitor.

What are the possible side effects that Lipitor may cause?
The list of Lipitor side effects includes:
- liver problems with the following symptoms: feeling weak or tired, upper belly pain, loss of appetite, dark urine, yellowing of eyes and skin;
- allergic reactions: swelling of the lips, face, throat, tongue causing breathing difficulties, skin reactions;
- muscle problems which may lead to some fatal kidney problems;
- vomiting, nausea;
- stomach pain;
and others.
Please call your doctor right away if anything from described above happens to you.

Are there any contraindications?
Lipitor is contraindicated in those with active liver disease (hepatitis, cholestasis, jaundice, and hepatic encephalopathy), inexplicable ALT or AST levels elevations, also in pregnant and nursing women. Before starting Lipitor therapy inform your doctor in case you have diabetes, kidney or thyroid problems, weakness or muscle pains, or you drink over 2 glasses of alcohol per day, as well as about all the drugs, herbal supplements and vitamins you use.
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